Jul 29, 2019 · Determining a suitable and reliable end-of-lifetime criterion for O-ring seals is an important issue for long-term seal applications. Therefore, seal failure of ethylene propylene diene rubber (EPDM) and hydrogenated nitrile butadiene rubber (HNBR) O-rings aged in the compressed state at 125 °C and at 150 °C for up to 1.5 years was analyzed and investigated under static conditions, using
Accelerated Aging. Justify test conditions and duration • Ambient temperature •FDA recommends 25°C •Aging temperature •Relative humidity •< 10-15°C T. g. for all polymers – Caution! With or Without Product •The presence of a device can stress a package and affect performance. Use of simulants is not uncommon.
Jan 1, 2017 · In this paper, thermal oxidation aging test, XPS and NMR analysis are used to analyze the aging mechanism of silicone rubber. Then the FEM contact model before aging and after aging is developed to study the influence of aging on sealing performance.
Sep 1, 2020 · For elastomer seals, both physical and chemical aging can deteriorate the seal performance. Physical aging involves reversible effects, e.g. relaxation through chain rearrangements [ 1 , 2 ], that lead to a loss of sealing force over time, but also irreversible effects such as loss of additives like plasticizer.
Snap caps are not as effective a seal as other closures. If the fit of the cap is very tight, the cap is hard to apply and may be subject to crack. If the fit is too loose, the seal is poor and the septum may dislodge. Screw caps are universal. Screwing the cap applies a mechanical force that squeezes the septum between the glass rim and the cap.
Crimp Seals for SPME, 11mm gold seal, magnetic (with 5mm center hole), red PTFE/silicone/red PTFE septum, septum diam. × thickness 11 mm × 1.0 mm, for use with CTC PAL and TriPlus autosamplers, pkg of 100 ea; find Supelco-SU860095 MSDS, related peer-reviewed papers, technical documents, similar products & more at Sigma-Aldrich
Vial crimp seals for SPME, 11 mm gold seal, magnetic (with 5 mm center hole), red PTFE/white silicone septum, septum diam. × thickness 11 mm × 1.3 mm, for use with CTC PAL and TriPlus autosamplers, pkg of 100 ea; find Supelco-SU860096 MSDS, related peer-reviewed papers, technical documents, similar products & more at Sigma-Aldrich
The benefits of deterministic container closure integrity methods are plentiful, and their usage can span the entire lifecycle of a product-package system, right from development of the package, assembly validation, to stability, to analysis of package integrity after distribution cycles.
Jul 1, 2019 · The Standard Test Method for Nondestructive Detection of Leaks in Packages by Vacuum Decay (ASTM F2338 - 09 (2013)) is versatile and can be used on flexible film and inner seals on rigid containers to assess the seal integrity of a water bottle to closure interface. • Bubble emission test. Internal pressure that seals can withstand is
3. Safety and Performance – The septa must not slide through the joint or pop-off during cannulation or when under pressure. • Pushing on a Precision Seal septum actually tightens the tapered plug to prevent movement. • The fl exible sleeve on the larger septa is oversized to make folding over glass joints easier and safer.
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Oct 5, 2023 · Capping, Sealing, and Temperature Cycling. A typical vial container closure system configuration has three major components: a vial, an elastomer stopper, and an aluminum seal with or without a flip-off button.5 Among these container closure system components, the elastomer stopper plays a critical role by deforming to seal the vial-stopper interface area either temporarily or permanently.
Oct 18, 2021 · Sections 7 and 8 investigate the effects of preload, surface anisotropy, and yield strength on sealing performance using this approach. 3. Geometrical Model of a Cone Seal. A cone seal is a type of static sealing structure that is widely used in aircraft engine pipelines (Fig. 2). The seal consists of three parts: cone part 1, cone part 2, and nut.
Mar 1, 2022 · The most economical and effective solution is to implement a hybrid approach addressing the packaging components, process, and seal integrity. First, the packaging components must be produced and verified to comply with the specifications verified during the package validation process. A comprehensive quality assurance program to inspect
Mar 1, 2021 · This review paper provides a comprehensive overview of the factors that affect the seal integrity in heat sealed flexible food packages, such as material properties, seal parameters, and
