Jul 11, 2017 · In a syringeless filter, the filter membrane, pre-filtration chamber, post-filtration storage vial, and cap are all part of one device (Fig 2). This design streamlines HPLC sample prep and minimizes the number of laboratory consumables. Filtration with a syringeless filter can be performed three times faster than with syringe filters. Using a syringeless filter simplifies the filtration process because you only need to add the sample to the outer chamber, place the plunger, and push.